What a gastrointestinal biopsy can tell us about Parkinson's disease?
Identifieur interne : 000122 ( Main/Exploration ); précédent : 000121; suivant : 000123What a gastrointestinal biopsy can tell us about Parkinson's disease?
Auteurs : A-G Corbillé [France] ; T. Clairembault [France] ; E. Coron [France] ; L. Leclair-Visonneau [France] ; C. Preterre [France] ; M. Neunlist [France] ; P. Derkinderen [France]Source :
- Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society [ 1365-2982 ] ; 2016.
Abstract
The intraneuronal inclusions called Lewy bodies and neurites, which represent the characteristic pathological changes in Parkinson's disease, are found in the enteric neurons in the great majority of parkinsonian patients. This observation led to a substantial amount of research over the last few years in order to develop a minimally invasive diagnostic procedure in living patients based on gastrointestinal (GI) biopsies.
DOI: 10.1111/nmo.12797
PubMed: 26914487
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">The intraneuronal inclusions called Lewy bodies and neurites, which represent the characteristic pathological changes in Parkinson's disease, are found in the enteric neurons in the great majority of parkinsonian patients. This observation led to a substantial amount of research over the last few years in order to develop a minimally invasive diagnostic procedure in living patients based on gastrointestinal (GI) biopsies.</div>
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